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Asian Journal of Research in Chemistry
Year : 2009, Volume : 2, Issue : 4
First page : ( 526) Last page : ( 528)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.

Spectrophotometric Methods for Simultaneous Estimation of Rabeprazole and Ondansetron from Combined Tablet Dosage Form

Kumar Vankar Kaushik1,*, Kumar Nayak Diptish1, Alankar Shrivastava2

1Lachoo Memorial College of Science and Technology, Pharmacy Wing, Jodhpur, Rajasthan (India) 342003

2B. R. Nahata College of Pharmacy, Mhow-Neemuch road, Mandsaur, Madhya Pradesh (India) 458001

*Corresponding Author E-mail: vankarkaushikkumar@yahoo.com

Online published on 13 March, 2013.

Abstract

Simple, accurate, economical and reproducible spectrophotometric methods for simultaneous estimation of Rabeprazole and Ondansetron in combined tablet dosage form have been developed. The developed method employs formation and solving of simultaneous equation using two wavelengths 284.4 nm and 302.0 nm for formation of simultaneous equation. This method obeys Beer's law in the employed concentration ranges. Results of analysis were validated statistically and by recovery studies.

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Keywords

Spectrophotometric estimation, Rabeprazole, Ondansetron.

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