|
|
|
|
|
|
|
|
|
|
Determination of Entacapone in Pharmaceutical Preparations by Liquid Chromatography Nagaraju P*, Narendra D, Kumar P Jitendra, Srinivas VDN, Padma SVN Hindu College of Pharmacy, Amaravathi Road, Guntur – 522 002 *Corresponding Author E-mail: raju_pharma35@rediffmail.com
Online published on 13 March, 2013. Abstract A reverse phase high performance liquid chromatographic method (HPLC) has been developed for the estimation of entacapone in its dosage forms using C18 column. The mobile phase (acetonitrile and 20mM potassium dihydrogen phosphate, PH 3.5) was pumped at a flow rate of 1 ml/min in the ratio of 80:20 and the eluents were monitored at 320 nm. The intra-and inter-day variation was found to be less than 2% showing high precision of the assay method. The mean recovery of the drug from the solution containing 200 or 300 μg/ml was 99.66 ± 1.20% indicating high accuracy. The proposed HPLC method may be used for determining entacapone in bulk drug samples or in pharmaceutical dosage forms Top Keywords Estimation, entacapone, tablets and HPLC. Top | |
|
|
|
|
║ Site map
║
Privacy Policy ║ Copyright ║ Terms & Conditions ║
 ║
|
|
|
812,856,788 visitor(s) since 30th May, 2005.
|
|
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
|
|
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.
|