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UV Spectrophotometric Method Development for the Determination of Domperidone in Tablet Formulation Kaushik Kailash Nath, Banerjee Saurabh Kumar* School of Pharmacy Technology and Management, SVKM's NMIMS University, Shirpur Campus, Shirpur, Dist: Dhule (M.S), India-425 405 *Corresponding Author E-mail: saurabhk77@gmail.com
Online published on 13 March, 2013. Abstract A simple, accurate, precise and reproducible method for the estimation of domperidone (DOM) in tablet dosage form was developed utilizing concept of UV spectrophotometry. Methanol was used as the solvent for domperidone. The UV spectrum of domperidone in methanol showed I max at 287.5 nm and Beer-Lambert law was obeyed in the concentration range of 6–36 μg/ml. Wavelength selected for estimation of domperidone was 287.5 nm. The result of analysis has been validated statistically. The recovery studies range from 99.5 to 100.1% confirmed the accuracy of the proposed methods. Top Keywords Domperidone, UV spectrophotometry. Top | |
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