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Synthesis and Biological Screening of Novel Aminoalkyl Substituted Azaphenothiazine Valentina P.*, Ilango K., Jain Deepak, Shukla Prerna Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM University, Kattankulathur -603 203 *Corresponding Author E-mail: valentina_7_srm@yahoo.com
Online published on 13 March, 2013. Abstract Some novel series of alkyl substituted azaphenothiazine were synthesized by condensation of 2-chloro-1-(10H-azaphenothiazin-10yl) ethanone with various amines. The synthesized compounds were confirmed by IR, 1HNMR and Mass spectroscopy. The bioavailabilities of the compounds were determined by Lipinski rule of 5 using customized software. All the compounds were screened for antimicrobial and sedative activity. Top Keywords Azaphenothiazine, Bioavailability, Antimicrobial activity, Sedative activity. Top | |
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