Microencapsulation: Is an advance Technique of Drug formulation for Novel Drug Delivery System
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The microencapsulation is a technique which is modern and widely used in the pharmaceutical industries foe different purposes. For the reduction of cost, to increase the stability of product, to mask unpleasant tastes, and to improve the release properties of drug in pharmaceutical industries this type of technique is generally used. The objective of this paper is to study the different techniques of microencapsulation of pharmaceutical ingredients by different processes. Microencapsulation is a rapidly expanding technology. In this process of form relatively thin coatings to tiny particles of solids or droplets of liquids and dispersions. The different types of microcapsules and microspheres are form from a wide range of wall materials like monomers and polymers. By the help of physicochemical properties of the core, the wall composition and the microencapsulation technique used, different types of particles can be obtained. It is economic feasibility of large-scale production, including operating and other miscellaneous things, such as transportation cost, regulatory cost. Microencapsulation often contain a basic understanding of the general properties of microcapsules, that is nature of the core and coating materials, the stability and release property of the coated materials and the microencapsulation methods. By mechanical method microencapsulation has been in the addition of oily medicines to tableted dosage forms. This has been used to avoid problems inherent in producing tablets from otherwise tacky granulations. This was accomplished through improved flow properties. Significances of is method, For Sustained or prolonged drug release formulation, For Masking test and odor of many drugs. For converting liquid into free flowing properties, drugs which are sensitive to Light, oxygen, moisture they are easily convert to stable form. Microencapsulation technologies are applied in any area of the industry for formulation.
Microcapsule, FDA-food and drug administration, Capsule coating, GRAS-generally recognized as safe, Coating technique, GMP-Good manufacturing practices.