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Research Journal of Science and Technology
Year : 2019, Volume : 11, Issue : 3
First page : ( 183) Last page : ( 185)
Print ISSN : 0975-4393. Online ISSN : 2349-2988.
Article DOI : 10.5958/2349-2988.2019.00028.7

Green Synthesis of Novel Chalcone Derivatives, Characterization and its Antibacterial Activity

Rani M. Sandhya*, Rohini C., Keerthi B. Sai, Mamata C.

Pulla Reddy Institute of Pharmacy, Sy. No 167, 168, Near Dundigal Airforce Academy, Annaram (V), Jinnaram (M), Medak Dist

*Corresponding Author E-mail: sandhya.madala@gmail.com

Online published on 31 December, 2019.

Abstract

In an effort to develop antimicrobial agents, a series of chalcones were prepared by Claisen-Schmidt condensation by trituration method. Appropriate acetophenones with appropriate aromatic aldehydes in the presence of aqueous solution of sodium hydroxide and ethanol at room temperature. The synthesized compounds were characterized by means of their IR, ‘H-NMR spectral data. All the compounds were tested for their antibacterial activities by the cup plate method.

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Keywords

Chalcone, synthesis, Antibacterial activity.

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