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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 9
First page : ( 1493) Last page : ( 1495)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00290.0

Anticoagulant activity of Calotropis gigantea leaves

Wadekar Jyoti B.1,*, Sawant Ramesh L.2, Sanklecha Kunal R.2, Ghodechor Amol S.2, Sable Priyanka B.2, Barkade Ganesh D.2

1Department of Pharmacognosy, Pad. Dr. Vithalrao Vikhe Patil Foundation's College of Pharmacy, Vilad Ghat, Ahmednagar-414111, India

2Department of Pharmaceutical Chemistry and P G Studies, Pad. Dr. Vithalrao Vikhe Patil Foundation's College of Pharmacy, Vilad Ghat, Ahmednagar, 414111, India

*Corresponding Author E-mail: jyotsfriend21@yahoo.com

Online published on 12 January, 2017.

Abstract

Calotropia gigantea (Asclcpiadacae) is widely growing plant and has been reported to possess multiple therapeutic properties like anti-pyretic, analgesic, anticonvulsant, anxiolytic, sedative, wound healing and antidiabetic. Chemical investigation of Calotropis gigantea report isolation of different type of photochemicals such as flavonoid, glycoside, terpenoid, steroid etc. However its anti thrombotic property has not been yet elucidated. Hence, in the present study we investigated the anti-thrombotic activity of aqueous and alcoholic extract of leaves of Calotropis gigantea in comparison with standard and normal saline as negative control.

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Keywords

Calotropis gigentea, flavonoid, Quick‘s method.

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