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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 9
First page : ( 1400) Last page : ( 1402)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00270.5

Study on Detecting the Adhesion Ability of Candida Species to Exofoliated Epithelial Cells

Aravind N1, Dr. Gopinath P2

1BDS 2nd year, Saveetha Dental College, Saveetha University, Chennai

2Senior Lecturer, Department of Microbiology, Saveetha Dental College, Saveetha University, Chennai

Corresponding Author E-mail:

Online published on 12 January, 2017.

Abstract

Candida species are considered as commensal yeast on cutaneous and mucocutaneous surfaces, particularly on gastro intestinal tract. It is one of the etiological agent of wide variety of infections that vary from superficial mycoses to life threatening systemic or deep seated infections. Adherence of candida to host cells is the first step in the infectious process, preceding colonization and invasion. Adherence protects the microorganism from being removed by natural host defence and clearance systems such as peristalsis and the bathing actions of fluids over mucosal surfaces. In the present study we have subjected 20 different isolates of Candida species to adherence to buccal epithelial cells. We observed 10/20 isolates were adhered onto the cells, which indicates that the ability to adhere on epithelical cells is a prerequisite to cause any mucocutaneous lesions by Candida spp.

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Keywords

Candida spp, Epithelial cells, adherence assay.

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