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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 6
First page : ( 735) Last page : ( 740)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00140.2

A green Hibiscus cannabinus oil emollient cream for potential topical applications

Banerjee Kaushita1, Pearline Diana1, Kamat Nandita1, Thiagarajan Narayanaswamy2, Thiagarajan Padma1,*

1School of Biosciences and Technology, VIT University, Vellore, 632014, India

2Material Science Division, National Aerospace Laboratories, Bangalore, 560017, India

*Corresponding Author E-mail: padmadk4@gmail.com

Online published on 21 July, 2016.

Abstract

A green emollient cream with Hibiscus cannabinus seed oil and an alkyl polyglucoside surfactant has been formulated. It can serve as biological alternatives to synthetic formulations that normally incorporate chemical constituents as surfactants and stabilizers mainly to increase consumer compliance in terms of textural and visual aesthetics. FAME analysis of the oil showed the presence octanoic and decanoic acids. The cream after formulation and ultrasonication, presented a smooth and soft appearance with visual and textural appeal. It showed a mean particle size of 138 nm with a zeta potential of -59.2 mV and an electrophoretic mobility of 0.000459 cm2/Vs. Its SEM image projected well dispersed oil globules in water. FTIR spectrum showed extensive hydrogen bonding. Accelerated stability tests under conditions of freeze thawing, heating cooling and centrifugation revealed no cracking, creaming or phase separation. Similar results were observed during the shelf life studies. It is concluded that this Hibiscus cannabinus cream can be utilized as an emollient base for loading cosmopharmaceutic ingredients for their topical delivery, without any toxicity concerns, as it is formulated from completely natural constituents.

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Keywords

Hibiscus cannabinus, Alkyl polyglucosides, Emollient cream, Topical applications.

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