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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 6
First page : ( 635) Last page : ( 640)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00121.9

Role of Coenzyme Q10 in human life

Pahari Sandip Kumar, Ghosh Somsubhra*, Halder Srijita, Jana Mayukh

Bharat Technology, Banitabla, Uluberia, Howrah, West Bengal, Pin-711316

*Corresponding Author E-mail: som_subhra_ghosh@yahoo.co.in

Online published on 21 July, 2016.

Abstract

Coenzymes are organic protein molecules enhance the action of enzyme. Being a Coenzyme now a day Co Q10 is used in different purposes like stress, Congestive heart failure, hypertension, parkinsonism etc. Ubiquinone and Ubiquinol are the effective Constituents of Co Q10. Ubiquinone and Ubiquinol are very useful as antioxidant Compound. Free radicals may be formed through natural human physiological processes as well as from the environment. They may be the result of diet, stress, smoking, alcohol, exercise, inflammation, drugs or exposure to sunlight and air pollutants Co Q10 has the remarkable effectiveness as vital intermediate on electron transport chain at Mitochondria. Coenzyme Q10 is Synthesized in intercellular region in the human body using tyrosine as fundamental building blocks. Q10 is a 1,4 benzoquinone, where Q refers to the quinone chemical group, and 10 refers to the number of isoprenyl chemical subunits in its tail. General dose of Co Q10 is 150 mg/day. Gastrointestinal disturbances have been reported as major adverse effect of this molecule till date. Current development in the production of Co Q10 is going on Continuously from plant, recombinant Escherichia Coli and metabolically engineered Escherichia Coli sources. Lots of research work is already going on this matter. In future if some research is needed on this Co-enzyme Q10 then this survey will stand as an informative document to researcher.

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Keywords

Coenzyme, Co Q10, Ubiquinone, Ubiquinol, Antioxidant.

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