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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 3
First page : ( 241) Last page : ( 244)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00044.5

To study Anti-inflammatory activity of 70% Methanolic Extract of Triumfetta rhomboidea: In Vitro Study

Thawkar B.*, Kale M., Oswal M., Maniyar K., Kadam K., Kamat S.

Department of Pharmacology, Konkan Gyanpeeth Rahul Dharkar College of Pharmacy and Research Institute, University of Mumbai, Karjat: 410201 Dist: Raigad, Maharashtra, India

*Corresponding Author E-mail: bspharma83@gmail.com

Online published on 18 April, 2016.

Abstract

Aim

To investigate and evaluate anti-inflammatory activity of 70% methanolic extract of Triumfetta rhomboidea by in vitro study.

Method

Antiinflammatory activity was studied by membrane stabilizing effect on human red blood cells (HRBC) and protein denaturation activity using 70% of methanolic extract of TR.

Result

The methanolic extract of TR having concentration 400μg/ml shows 34% of membrane stabilizing activity whereas same concentration shows 208% of protein denaturation activity by protecting from lysis.

Conclusion

From the study it can be said to be the anti-inflammatory activity of Triumfetta rhomboidea is due protein denaturation activity and membrane stabilizing activity.

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Keywords

Triumfetta rhomboidea, Protein denaturation activity, membrane stabilization, antiinflammatory activity, In vitro study.

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