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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 11
First page : ( 1927) Last page : ( 1929)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00394.2

Comparison of aceclofenac and combination (Aceclofenac + Thiocolchicoside) therapy in acute low back pain patients

Aparna P.*, Mrs. Geetha P., Dr. Shanmugasundaram P.

Vels University, Chennai

*Corresponding Author E-mail: aparnaaz1@gmail.com

Online published on 2 March, 2017.


A prospective observational assessment of pain severity for acute low back pain patients conducted over a period of 12 months in ESI hospital, ayanavaram. In this study, 200 patients with acute low back pain were included and out of this 100 patients were given Aceclofenac and remaining 100 were given combination (Aceclofenac + Thiocolchicoside) therapy and the patients were selected based on the inclusion and exclusion criteria. During the study period, 26 patients from group A and 21 patients from Group B did not come for follow-up. Out of 200 patients, 46.5% were males and 53.5% were females. The intensity of the pain relief was 8.3 on day 0, 6.5 on day 3 and 3.9 on day 7 for Aceclofenac and 8.1 on day 0, 5.5 on day 3 and 2.5 on day 7 for combination (Aceclofenac + Thiocolchicoside) therapy. Out of 153 patients, 21 of them had no change, 10 of them had poor, 27 of them had moderate 10 of them had good and 06 of them had excellent efficacy for Aceclofenac therapy and 05 of them had no change, 09 of them had poor, 32 of them had moderate, 23 of them had good and 10 of them had excellent efficacy on combination (Aceclofenac + Thiocolchicoside) therapy. In this study we found that decrease in severity of pain at discharge assessed by VAS was more pronounced within patients receiving Aceclofenac + Thiocolchicoside as compared to patients receiving Aceclofenac therapy.



Pain, Aceclofenac, Thiocolchicoside, Low back pain, Therapy.


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