Users online: 7937    [ij] [ij] [ij] 
Email id

Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 10
First page : ( 1786) Last page : ( 1788)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00361.9

Cortisol in saliva of uncontrolled diabetes patients and adrenal stress index

 Nandakumar1,*, Dr. Gheena S.2

1BDS 2nd Year, Saveetha Dental College and Hospitals, Chennai-77

2Department of General Pathology, Saveetha Dental College and Hospitals, Chennai-77

*Corresponding Author E-mail: nandudpi2014@gmail.com

Online published on 2 March, 2017.


Aim and Objective

To do a review study on the level of cortisol in saliva of diabetic patients as an estimate of the stress levels and associated adrenal stress index.


Cortisol is a steroid hormone in the glucocorticoid class of hormones, and is produced in humans by the Zona fasiculata of the adrenal cortex within the adrenal gland. It is released in response to stress and low blood glucose concentration. It functions to increase blood sugar through gluconeogenesis to suppress the immune system and to aid in the metabolism of fat, protein and carbohydrates and also decreases bone formation. Chronic hypoglycemia can impair normal adrenal function by repetitive overstimulation of cortisol production. Recurring exposure to high cortisol will impair insulin activity, and invariably lead to insulin resistance and beta-cell exhaustion. The ASI panel investigates the insulincortisol relationship under real-life conditions to allow targeted and meaningful interventions. This panel is useful in the following clinical situations: rapid weight gain and obesity, deranged blood lipids, sugar blues, early diabetes and associated emotional disturbances.


Awareness about the actual cause of the diabetes remains unknown. This review study aims at creating awareness among the people.


║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
446,227,280 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.