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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 10
First page : ( 1585) Last page : ( 1587)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00312.7

Detection of carbapenemase resistance among clinical isolates of Klebsiella pneumoniae

Ahad Mohammed1, Dr. Gopinath P2

1BDS 2nd year, Saveetha Dental College, Saveetha University, Chennai

2Senior Lecturer, Department of Microbiology, Saveetha Dental College, Saveetha University, Chennai

Corresponding Author E-mai:

Online published on 2 March, 2017.

Abstract

Carbapenems are considered to be the choice for the therapeutic management of multidrug resistant gramnegative bacterial infections. Currently, the spread of carbapenem-resistant bacteria are in alarming state due to the limited choice in antibiotics for treating infections caused by them. We detected the antibiotic susceptibility pattern using most routinely used antibiotics and found higher percentage resistance pattern and also checked for the presence of carbapenemase in our isolates by Modified Hodge test method and we found there were no isolates found to be positive for carbapenemase production. We conclude that more number of isolates needs to be screened for the presence of such resistance mechanism to validate the actual resistance status and prompt treatment.

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Keywords

Klebsiella pneumoniae, Modified Hodge Method, Carbapenemase.

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