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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 10
First page : ( 1547) Last page : ( 1551)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00303.6

Phytochemical screening, phenolic, flavonoids, carotenoids contents and antioxidant activity of folkloric Memecylon edule roxb.

Kumar Tekeshwar1,*, Jain Vishal2

1Assistant Professor, Apollo College of Pharmacy, Anjora, Durg, 491 001, CG, India

2Assistant Professor, University Institute of Pharmacy, Pt. Ravishankar University, Raipur, 492 010, CG, India

*Corresponding Author E-mail: tekeshwarverma@gmail.com

Online published on 2 March, 2017.

Abstract

Memecylon edule Roxb. (Melastomataceae) is a shrub or a small tree widely habitat in Orissa, Assam and Western Peninsula. By tradition, plant is used in the treatment of snake bite, skin and stomach disorder. However, information about unexplored phyto-constituents and antioxidant properties remains to be elucidated. To evaluate the antioxidant potential of the ethanolic and aqueous root extract of Memecylon edule (M. edule) Roxb. Ethanolic and aqueous root extract of M. edule were prepared and screened for total phenolics, flavonoids, carotenoid content and in-vitro antioxidant activity. Extracts of M. edule contents tannin, flavonoid, triterpenes and phenolic compounds. Total phenolic components for the ethanolic and aqueous extract of M. edule is equivalent to 94±1.4 and 20.64±0.26 mg of gallic acid and flavonoid content was 21.56±3.2 and 5.95±0.18 mg of quercetin respectively. Total carotenoid contents of the ethanolic extract and aqueous extract of roots M. edule are 43.12±0.75μg and 23.12±0.55μg respectively. The IC 50 values were found to be 77.5±0.78μg/ml and 61±0.58μg/ml in DPPH and in superoxide radical scavenging 894±5.4μg/ml and 679±2.4μg/ml for ethanolic extract of M. edule and standard respectively. For reducing power assay the EC50 values were found to be 74±1.4μg/ml and 55±0.97 μg/ml of ethanolic extract of M. edule and ascorbic acid respectively. The observed antioxidant ability of M. edule may be due to abundant presence of phenolic contents. So our findings provide evidence that the crude ethanolic extract bared antioxidant activity and this justifies its ethnic uses in folkloric medicines.

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Keywords

Memecylon edule, Poly phenol, Reactive oxygen species, FRAP, SRSA, DPPH radical.

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