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Research Journal of Pharmacy and Technology
Year : 2015, Volume : 8, Issue : 5
First page : ( 597) Last page : ( 610)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2015.00099.2

Indian Medicinal Plants Used for Treatment of Rheumatoid Arthritis

Kumar Shyama S.1, Bhosle Divya1, Janghel Akshay1, Deo Shraddha1, Raut Parijeeta1, Verma Chetan1, Agrawal Mukta1, Amit Nisha2, Sharma Mukesh1, Giri Tapan3, Tripathi D. K.1,  Ajazuddin1, Alexander Amit1,*

1Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, India, 490024

2Ex-employee, Kalyan PG College, Sector 7, Bhilai, Chhattisgarh, India

3NSHM College of Pharmaceutical Technology, NSHM Knowledge Campus, Kolkata Group of Institutions, 124 BL Saha Road, Kolkata-700053, West Bengal, India

*Corresponding Author E-mail: itsmeamitalex@gmail.com

Online published on 25 June, 2015.

Abstract

Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology and is mainly characterized by the progressive erosion of cartilage leading to chronic polyarthritis and joint distortion. Although the exact pathogenesis of the disease has yet not been elucidated, however, studies suggest that cellular proliferation of synoviocytes result in pannus formation which damages the cartilage and bone. Recent reports also support the role of free radicals in its pathogenesis. Apart from the conventional treatment strategies using nonsteroidal anti inflammatory drugs, disease modifying antirheumatic drugs and glucocorticoids, newer and safer drugs are continuously being searched, as long term usage of these drugs have resulted in adverse effects. Alternative medicine provides another approach for treatment of RA and currently a number of medicinal plants are under scientific evaluation to develop a novel drug. There is a dire need to investigate the complete therapeutic potential and adverse effects, if any, of these herbals for providing newer and safer treatment options with minimum side effects. In this paper we have tried to explore various Indian ancient Ayurvedic, Unani and Tibet, as also some Chinese and Korean, herbals for their potential to treat RA.

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Keywords

Rheumatoid arthritis, joint distortion, herbal drugs, therapeutic potential, alternative medicine.

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