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Research Journal of Pharmacy and Technology
Year : 2015, Volume : 8, Issue : 5
First page : ( 517) Last page : ( 519)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2015.00086.4

GC-MS/MS Study of Parthenium hysterophorus L(N. Am) stem, Antimicrobial activity

Krishnaveni M.1,*, Kalaivani M.2, Banu C. Ragina2, Kumari G. Krishna2

1Assistant Professor, Department of Biochemistry, School of Bio-Sciences, Periyar University, Salem

2M.Phil Students, Department of Biochemistry, School of Bio-Sciences, Periyar University, Salem

*Corresponding Author E-mail: logan.consolidated@gmail.com

Online published on 25 June, 2015.

Abstract

15 species of Parthenium are available under this genus. Parthenium hysterophorus belong to the family of Asteracea. Since, plant forms a fundamental raw material for the development of therapeutic drug, the phytocomponents of plants are vital tool for the treatment and cure. So, the present work was decided to study the components in ethanol extract of Parthenium hysterophorus stem through GC-MS/MS and its antimicrobial activity. The results of GC-MS/MS showed highest peak for Aciphyllene, Stigmasteryltosylate, Benzophenone, Stigmasterol, 4-Nitrophenyl laurate. Compounds such as Azulene, 1,2,3,5,6,7,8,8a-octahydro-1,4-dimethyl-7-(1-methylethenyl)-, [1S-(1α,7α,8aβ)]-, Bicyclo[3.1.0]hexan-2-one, 1,5-bis(1,1-dimethylethyl)-3,3-dimethyl-, 1,2-Benzenediol, mono(methylcarbamate), 2,5-Dihydroxyacetophenone, bis(trimethylsilyl) ether, 12-Tridecynoic acid, methyl ester, Phenol, 3,4-dimethoxy-, 4-Acetoxy-3-methoxystyrene, Benzoic acid, 4-methyl-2-trimethylsilyloxy-, trimethylsilyl ester, 12-Tridecynoic acid, methyl ester, Tetradecanoic acid shows moderate peak area percent. The results of antimicrobial activity shows that antimicrobial activity was observed with Escherichia coli, Aspergillus niger, Candida albicans while, Staphylococcus aureus showed no zone of inhibition.

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Keywords

Antibacterial, Antifungal, Parthenium, Phytocontituents, GC-MS/MS.

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