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Research Journal of Pharmacy and Technology
Year : 2015, Volume : 8, Issue : 10
First page : ( 1417) Last page : ( 1422)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2015.00255.3

Phytochemical and antimicrobial properties of Cardiospermumhali cacabum and Solanum nigrum

Vaishvedhidha M.U, Ezilrani P, Christopher Godwin J*

Molecular and Microbiology research laboratory, School of biosciences and technology, VIT University, Vellore-632014, Tamil Nadu, India

*Corresponding Author E-mail: godwinj@vit.ac.in

Online published on 2 December, 2015.


Aqueous and methanolic leaf extract of Cardiospermum halicacabum and Solanum nigrum was examined for their phytochemical and antimicrobial properties. The preliminary phytochemical screening of extracts of herbs showed the presence of bioactive components like carbohydrates, proteins, amino acids, flavonoids, terpenoids, saponins, phytosterols, phenols and tannin. The extract was also evaluated for antimicrobial activity against medically important bacteria like Escherichia coli (NCIM2931), Staphylococcus aureus (NCIM2079), Bacillus subtillis (NCIM2106), Pseudomona sputida; fungus like Aspergillus niger and yeast Saccharomyces cerevisiae. It was observed that all the specimens selected were effective against the tested microorganisms in one extract or the other. This means the extracts were capable of inhibiting both gram negative bacteria and gram positive bacteria and it was also effective against fungus. It did not show any activity against the yeast. It was observed that the methanol extracts had wider range of activity on these organisms than the aqueous extracts. It was also observed that the extraction method one showed better results and inhibition.



Antimicrobial activity, extract, phytochemicals, microorganisms, methanol, aqueous.


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