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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 6
First page : ( 2597) Last page : ( 2600)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00462.X

Synthesis and Antibacterial activity of some newer Benzimidazole derivatives

Kumari Pooja*, Umakant, Sharma Gyanendra

Department of Pharmaceutical Chemistry, Rajiv Academy for Pharmacy, N.H. #2, Mathura Delhi Road, P.O. chhatikara, Mathura, Uttar Pradesh (India) 281001

*Corresponding Author E-mail: kr.pooja007@gmail.com

Online published on 4 July, 2020.

Abstract

A series of some newer benzimidazole derivatives were synthesized and evaluated for their anti-bacterial activity. Some of new benzimidazole derivatives are derived from the parent compound. The result shows all the compounds have low micromoler minimal inhibitory concentration (MIC) gives a good antibacterial activity against Gram-positive or Gram-negative bacteria. Benzimidazole is the heterocyclic compound formed from benzene ring and five-member ring containing nitrogen and its derivatives are wide interest because of their diverse biological activity and clinical applications.

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Keywords

Benzimidazole, newer derivatives, antibacterial activity, spectral analysis.

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