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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 4
First page : ( 2053) Last page : ( 2058)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00369.8

Recent Advances in Liposome

Chauhan Shikha Baghel*, Gupta Vaishnavi

Assistant Professor, Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Noida, Uttar Pradesh, India

*Corresponding Author E-mail: shikha.pharma@gmail.com

Online published on 30 April, 2020.

Abstract

Liposomes as artificial colloidal vesicular structure having hydrophilic core in a lipid bilayer membrane became one of the most tremendously explored drug delivery system. These spherical vesicles consist of amphiphilic molecule like cholesterol, sterols and can be used to deliver both hydrophilic drugs as well as lipophilic drug. These vesicles are differentiated on the basis of size, composition, method of preparation and application. Liposomes are biodegradable, nonimmunogenic, biocompatible, provide targeted and prolonged release, change pharmacokinetic and pharmacodynamic attribute of drug, they find wide clinical application as diagnostic, antimicrobial, anticancer, vaccine adjuvant and cosmetics. Expanding application show promising sign for future development in liposome. The present review provides information about liposome in drug deliver, their composition, structure, different method of preparation, various types of liposome, clinical applications of liposome, strategies, marketed formulation.

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Keywords

Liposome, classification, method, application, characterization.

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