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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 4
First page : ( 2013) Last page : ( 2018)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00362.5

Holarrhena antidysenterica Linn. – A Review

Gopinath G, Thirumal M*, Kumar P. R.

Department of Pharmacognosy, SRM College of Pharmacy, Kattankulathur-603203

*Corresponding Author E-mail: thirumal_sel@yahoo.co.in

Online published on 30 April, 2020.

Abstract

Holarrhena antidysenterica belongs to the family Apocynaceae is commonly known as kurchi in Hindi, Tellicherry bark in English is a small deciduous tree which is distributed throughout the world and in India, it is found in dry forests. In Indian traditional medicine, H. antidysenterica is popularly used as a medication for dysentery, diarrhoea and intestinal worms. Plant parts such as bark are used to treat anti-microbial, anti-inflammatory, analgesics, amoebiasis, chronic bronchitis, locally for boils, ulcers; a decoction of the bark is used in bleeding and piles. The phytochemicals present in the plant include coumarins, ergosterol, flavonoids, phenolic acids, resins, saponins, steroidal alkaloids, tannins, triterpenoids. Pharmacological studies include anti-amnesic, neuroprotective, acetylcholinesterase inhibitory, anti-diabetic, anti-urolithic, antibacterial activity, anti-haemorrhoidal, analgesic activity, anti-inflammatory, anti-malarial, anti-diarrhoeal, anti-mutagenic, antihypertensive activity, antioxidant/free radical scavenging property, diuretic activity, anti-amoebic, anthelminthic, anti-microbial and anti-MRSA properties of Holarrhena antidysenterica. This review article explored the detailed investigation of the botanical description, phytochemistry and pharmacological actions of Holarrhena antidysenterica to afford an objective for further research.

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Keywords

Holarrhena antidysenterica, alkaloids, anti-amoebic, anti-diarrhoeal.

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