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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 4
First page : ( 1951) Last page : ( 1956)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00351.0

Antihyperglycemic Status of Coccinia grandis: An Extensive Overview

Sunny Betsy1,*, Dr. Mathews Manju Maria2, Joseph Dhanish3, Mathew Flowerlet4, George Junia1, Varghese Bimi1

1Department of Pharmaceutics, Nirmala College of Pharmacy, Muvattupuzha, Kerala

2Associate Professor, Department of Pharmaceutics, Nirmala College of Pharmacy, Muvattupuzha, Kerala

3Assistant Professor, Department of Pharmaceutics, Nirmala College of Pharmacy, Muvattupuzha, Kerala

*Corresponding Author E-mail: betsysunnye@gmail.com

Online published on 30 April, 2020.

Abstract

Plants are an exemplary source of medicine and have been used in healthcare since time immemorial. They are an efficacious remedy for multiple ailments. Coccinia grandis belonging to family Cucurbitaceae is a reservoir of medicinal properties. It is being regarded as a universal panacea in Ayurvedic medicines. Extracts made from the various parts of the plant mainly leaf and fruit have significant analgesic, anti-inflammatory, antimicrobial, antidiabetic, antioxidant, hepatoprotective, anticancer, mutagenic activity, etc. in different animal models. Coccinia grandis contain copious amounts of phytoconstituents like flavonoids, saponins, glycosides, alkaloids, phenols, etc. which heavily contribute to the diverse pharmacological activities. In this study, the focus is given to Coccinia grandis as a better herbal substitute for synthetic counterparts in antihyperglycemic therapy.

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Keywords

Coccinia grandis, Cucurbitaceae, ayurvedic medicine, animal models, antihyperglycemic.

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