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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 9
First page : ( 4550) Last page : ( 4558)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00783.2

Recent Approaches in Transdermal Drug Delivery System

Stanekzai A1,*, Sudhakar CK2, Zhakfar AM.3, Karan Vikrant. Singh4,5

1Research Scholar, Lovely Institute of Technology (Pharmacy), School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab and Lecturer at Kabul University, Faculty of Pharmacy, Department of Pharmaceutics

2Assistant Professor at Lovely Institute of Technology (Pharmacy), School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab

3Associated Professor at Kabul University, Faculty of Pharmacy, Department of Pharmaceutics, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab

4Research Scholar, Lovely Institute of Technology (Pharmacy), School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab

5Research Scholar, Lovely Institute of Technology (Pharmacy), School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab

*Corresponding Author E-mail: sudhakar.20477@lpu.co.in

Online published on 24 December, 2019.

Abstract

Transdermal drug delivery has been applied as a safe and efficient delivery system since 1981. TDDS recently accessible to dominate the problems of drug delivery over the oral route. Transdermal film is a therapeutic adhesive film which is used on the skin to deliver a particular amount of drug over the skin as well as systemic circulation. Development of an effective TDDS is dependent to physicochemical properties of drug, excipients and manufacturing possesses. For achieving systemic effect, many new carriers have been established such as Liposomes, Niosomes, Transfersomes, Cubosome and Ethosomes, an enormous request for pharmaceutical and cosmeceutical industry, it has capability to controlled the release of active ingredient, enhance consistency and bioavailability. In this review, we have summarized many physicochemical approaches for transdermal drug delivery system, containing classification of TDDS, enhancing the permeability of drug over the skin, marketed formulation and application of transdermal drug delivery system.

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Keywords

TDDS, Enhancing Permeability, Classification, Evaluation Parameter, Marketed Formulation.

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