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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 9
First page : ( 4443) Last page : ( 4446)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00766.2

Detection of HPV-16 and HSV-2 among women with Chronic Cervicitis in Baghdad City

Hussein Areej Atiyah1,*, Khashman Basim Mohammed2

1University of Diyala, College of Medicine, Department of Microbiology, Iraq

2University of Baghdad, Iraqi National Cancer Research Center, Iraq

*Corresponding Author E-mail: areej.2002@yahoo.com

Online published on 24 December, 2019.

Abstract

Background

Cervicitis is inflammation of cervical, it's associated with most commonly of sexually transmitted viruses such as human papilloma virus and herpes simplex virus.

Objective

To estimate the frequency of infection with human papilloma virus -16 and herpes simplex virus-2 in women with cervicitis and related with age and severity in Baghdad city.

Patients and Methods

Retrospective study was conducted in 50 formalinfixed paraffin embedded tissues from women with chronic cervicitis were collected from the archives of the Department of Pathology, Teaching Laboratories in Baghdad Medical City during the period from February 2018 till April 2018. Immunohistochemical staining of human papilloma virus -16 and herpes simplex virus -2 were determined in study group.

Results

The expression of human papilloma virus -16 and herpes simplex virus -2 in women tissues with chronic cervicitis was 40% (20 out of 50). Most positive viral cases 10(50%) and 12(60%) were recorded in age group (20–35) years respectively; non-significant differences was noticed between viral infection and age of patients, majority of women were CIN1 44(88%) while other in CIN2 6(12%) also non-significant differences was found between viral infection and stage of chronic cervicitis.

Conclusion

Infection rate of human papilloma infection -16 and herpes simplex infection -2 in this investigation were lower than different reports from various nations, this could be connected with the social conduct of ladies around there, where they generally have just a single accomplice for the duration of their life.

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Keywords

Cervicitis, human papilloma virus -16, herpes simplex virus -2, immunohistochemistry.

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