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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 9
First page : ( 4400) Last page : ( 4404)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00757.1

Synthesis, Characterization and Antibacterial effect of Neem Oil Nanoemulsion

Deeksha K., Pavya, Hari Sowmya*

Department of Bio-Engineering, VISTAS, PV Vaithiyalagam Rd, Velan Nagar, Krishnapuram, Pallavaram, Chennai, Tamil Nadu-600117

*Corresponding Author E-mail: sowmya.se@velsuniv.ac.in

Online published on 24 December, 2019.

Abstract

The nanoemulsion study deals with the formulation and characterization of bio based oil in water nanoemulsion and its potential antimicrobial activity. The resistance of the bacteria and fungi to the numerous antimicrobial agents constitutes one of the great challenges in the treatment of infections and finding new sources of substances with antimicrobial properties. Emulsions are used to stabilize and increase the antimicrobial efficacy of oils in aqueous solutions. Eucalyptus oil and neem oil used as antibacterial agent in pharmaceutical products. This study deals with nanoemulsion formulation with neem oil, tween 20, by high, ultrasonication and the droplet size is confirmed by DLS (Dynamic light scattering). Smaller droplets provide better distribution of the oil. The effective anitimicrobial activity against pathogens Pseudomonas aeruginosa and Bacillus subtilis.

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Keywords

Nanoemulsion, ultrasonication, antimicrobial agents, infection, DLS.

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