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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 7
First page : ( 3507) Last page : ( 3510)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00596.1

Anti-inflammatory Activity of Turmeric Oil Mediated Silver Nanoparticles

Das Anubhav1, Roy Anitha2,*, Rajeshkumar S.2, Lakshmi T.2

1Graduate Student, Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Tamil Nadu, India

2Associate Professor, Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Tamil Nadu, India

*Corresponding Author E-mail: anitharoy2015@gmail.com

Online published on 24 December, 2019.

Abstract

Background

Curcuma longa is a medicinal plant commonly known as turmeric and well known for its medicinal properties. Curcumin, the main constituent of turmeric,. Curcumin is responsible for the biological activities of turmeric. Curcumin has potent anti-inflammatory activity.

Aim

In the present study, antiinflammatory activity of turmeric oil mediated silver nanoparticle was Carried out.

Materials and Methods

Turmeric oil was obtained from Synthite Industries Limited, Kerala as a gift sample and silver nanoparticle was prepared using Turmeric oil. The synthesized nanoparticles solution was preliminarily characterized by using UV-visible spectroscopy. The color change in reaction mixture (Silver nitrate solution + turmeric oil) was recorded by visual observation. The results were recorded for the graphical analysis.

Results

The greatest effect of AgNPs (150 μg/mL) was found to be more than standard diclofenac sodium.

Conclusion

It may be concluded from this study that turmeric oil mediated silver nanoparticles can be used as potential source of anti inflammatory agent.

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Keywords

Curcuma longa, curcuminoids, anti-inflammatory, Bovine Serum albumin, albumin denaturation assay.

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