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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 7
First page : ( 3189) Last page : ( 3196)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00536.5

Novel Approaches in Nanoparticulate Drug Delivery System to Overcome Human Immunodeficiency Virus.

Roopa M, Mohan Arthi*

Department of Pharmaceutics, 12/1, Krupanidhi College of Pharmacy, Chikkabellandur, Carmelaram Post, Varthur (H), Bangalore, Karnataka-560035

*Corresponding Author E-mail: roopachandra94@gmail.com, Artimohan89@gamil.com

Online published on 24 December, 2019.

Abstract

The development of antiretroviral medication has considerably modified the perception of Human Immunodeficiency virus/Acquired immunodeficiency syndrome (HIV/AIDS) as a fatal to a last stage manageable sickness. The convenience and organization of antiretroviral medicinal consideration has essentially diminished mortality and horribleness related to HIV and AIDS. Antiretroviral drug deficiency remains a serious drawback in underserved populations worldwide. Partnerships among pharmaceutical corporations, tutorial investigators and government and nongovernment agencies is necessary to boost access to life-saving regimens. Nanomedicine opens new restorative roads for assaulting viral diseases and for enhancing treatment achievement rates. Significantly, nanomaterials like dendrimers and numerous other inorganic nanoparticles like gold, silver, zinc, and iron can be utilized for HIV treatment. Moreover, nanoparticles could best go about as adjuvants, convoys throughout vaccine delivery, nanomedicine could also be an appropriate methodology in HIV/AIDS treatment by methods for offering lower dose and aspect impact, better patient-to-persistent consistency and HIV diagnosis. This article explores the varied applicable methods for delivery of antiretroviral drugs within the style of liposomes, dendrimers, solid lipid nanoparticles, microspheres and polymeric nanoparticles. These approaches of delivery are verified to supply innovative and direct delivery of antiretroviral medication by enhancing the therapeutic effectiveness, targeting the location of action and increasing the activity and safety of the medication.

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Keywords

Antiretroviral drug, drug delivery, HIV, nanocarriers, nanomedicine.

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