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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 3
First page : ( 1463) Last page : ( 1472)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00243.9

Nano Structure of Hydroxyapatite and its modern approach in Pharmaceutical Science

Singh Sushma*, Pal Abhisek, Mohanty Sangeeta

School of Pharmaceutical Sciences, Siksha-O-Anusandhan Deemed to be University, Bhubaneshwar, Orissa, India

*Corresponding Author E-mail: thakuri.sushma15@gmail.com

Online published on 18 May, 2019.

Abstract

Nanotechnology has wide applications in many fields, especially in the field of biological sciences and medicines. In this review, study is mainly focused on the nanostructure of hydroxyapatite and its various applications in the field of pharmaceutical science. Nano hydroxyapatite has proved to be a boon in the field of biomedical science because of its property such as-biocompatibility, bioactivity, nontoxicity, noninflammatory, osteoconductivity. From this review one can definitely assemble knowledge about the making and characterization of Nano hydroxyapatite and its uses in the field of biomedical platform. This paper also collects information about the hydroxyapatite prepared from plant source by green synthesis mainly used for the study of antimicrobial action. Hydroxyapatite being bioactive in nature is highly compatible with the tissues and bones and has a very wide spectrum of activity to treat highly infectious disease such as cancer. Therefore the study is focused on its applicability to treat diseases such as bone cancer, bone diseases, microbial infection etc, also involving discussion on nanohydroxyapatite synthesis and its various applications.

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Keywords

Hydroxyapatite, Nano structure, Calcium phosphate, Remineralising, Green synthesis.

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