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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 3
First page : ( 1181) Last page : ( 1184)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00195.1

Pharmacological Evaluation of Leaf Extract of Terminalia bellerica with Moringa oleifera for its Synergistic Action on Anti-diabetic Activity and Anti-inflammatory Activity in Rats

Karishma Sk.*, Lakshmi K., Tony D. Eswar, Babu A. Narendra, Nadendla Rama Rao

Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Guntur. Andhra Pradesh

*Corresponding Author E-mail: karishushaik11@gmail.com

Online published on 18 May, 2019.

Abstract

Aim and Objective

To evaluate the pharmacological action of leaf extract of Terminalia bellerica with Moringa oleifera for its synergistic action on Anti Diabetic activity and Anti-inflammatory activity in rats.

Methodology

The Pharmacological evaluation of standardized aqueous extract of the leaves of Terminalia bellerica with Moringa oleifera was carried by using the following Stimuli models: a)Antidiabetic activity by Streptozotocin Induced Diabetes, b) Anti-inflammatory activity by Egg Albumin Induced Paw Edema.

Results

The parameters of various activities to assess anti diabetic and anti inflammatory activities were evaluated and found That, The combination of extracts possess a better response then alone.

Conclusion

The aqueous leaf extract of the combination of Terminalia bellerica with Moringa oleifera has shown significant anti diabetic and anti-inflammatory activities when compared with standard and extract alone.

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Keywords

Terminalia bellericaMoringa oleifera, Anti diabetic activity, Anti-inflammatory activity, Digital Plethysmometer, Glucometer.

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