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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 2
First page : ( 827) Last page : ( 830)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00143.4

Evaluation of In vivo Wound Healing Activity of dried leaf Ethanolic extract of Indigofera tinctoria on Albino Wistar Rat

Manimekalai P.1,*, Gurumoorthy M.1, Dhanalakshmi R.2

1Swamy Vivekanandha College of Pharmacy, Tiruchengode, Namakkal (DT)

2Edayathangudy G.S Pillay College of Pharmacy, Nagapattinam-600117

*Corresponding Author E-mail: mekalaivel@gmail.com

Online published on 18 April, 2019.

Abstract

Aim of the present study was to evaluate the wound healing properties of ethanolic extract of Indigofera tinctoria on Albino wistar rat. The preliminary Phytochemical evaluation was carried out by standard methods. Burn was induced in wistar rat divided in to five groups as follow: Normal control Group-I received petroleum jelly. Group II Received Silver sulphadiazine-1%w/w, Group III received 5% extract of Indigofera tinctoria ointment, Group IV received 10% w/w Indigofera tinctoria ointment and Group V received 20% w/w Indigofera tinctoria ointment topically twice daily for 16 days. The topical application of 20% w/w Indigofera tinctoria ointment, shows significant (P<0.001) reduction in the wound breaking strength when compared to III received 5% extract of Indigofera tinctoria ointment but not comparable with Silver sulphadiazine-1%w/w treated group.

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Keywords

Wound healing activity, Indigofera tinctoria, Hydroxyproline, Epithelialization.

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