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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 2
First page : ( 764) Last page : ( 772)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00135.5

Povidone-Iodine binded with Natural Herb of Tridax procumbens to increase the Antimicrobial Activity

Andal Perumal*, Tamijselvy S., Surya S.

Department of Chemistry, School of Basic Sciences, Vels Institute of Science Technology and Advanced Studies, Pallavarm, Chennai-600117, Kancheepuram, District, Tamil Nadu, India

*Corresponding Author E-mail: andalprithu.sbs@velsuniv.ac.in

Online published on 18 April, 2019.

Abstract

The new antimicrobial skin preparations useable to disinfect a surgical site for surgery. The antimicrobial skin-preparation formula includes povidone-iodine & Extract Tridax procumbens. The new pre-operative skin-preparation quickly and effectively kills microorganisms when applied to the surgical site. The skin-preparation continues to effectively inhibit microorganism growth in the applied area over an extended period of time. The role of the newly developed formulations of povidone-iodine preparations, its antimicrobial activity, the possibility of impairing the wound healing process, the role of povidone-iodine in the problem of growing resistance against antibiotics & antiseptics. Iodine and its antibacterial properties have been used for the prevention or management of wound infections for over 150 years. However, the use of solutions (tincture) of iodine has been replaced by the widespread use of povidone-iodine, a water-soluble compound, which is a combination of molecular iodine and polyvinylpyrrolidone. The resultant broad spectrum of antimicrobial activity is well documented and its efficacy, particularly in relation to resistant micro-organisms. The antibacterial activity of Tridax procumbens performed by using agar well diffusion method showed a result showcasing an effective limit when as opposed pseudomonas vulgaris for ethanol being used as solvent for extract. In Tridax procumbens leaves extract terminate most propitious source.

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Keywords

Polyvinylpyrrolidone, microorganism, disinfectants.

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