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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 2
First page : ( 745) Last page : ( 749)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00132.X

The OGG 1 Ser326cys gene Polymorphism and breast tumor risk of Iraqi Women

Nsaif Ghufran Saad1,*, Abdallah Amer Hassan1, Ahmed Najwa Shehab2

1Chemistry Department, College of Science, University of Mustansiriyah, Baghdad-Iraq

2Biotechnology Research Center, University of Al-Nahrian, Baghdad-Iraq

*Corresponding Author E-mail: almutar.haydar@gmail.com

Online published on 18 April, 2019.

Abstract

The purpose of this study was to test the association between human 8-oxoguanine glycosylase 1 (OGG1) gene polymorphisms to the breast tumor in the Iraqi women. One-hundred-three Sample were obtained from patients with breast cancer (28 women malignant breast tumor patients group), (28 control group), (28 benign group) and (19 Radiotherapy group) of (30–59) years old in Al-Eluia hospital for woman care, oncology teaching hospital between September 2016 to January 2017. The results showed that there was a significant difference when comparing the control with benign and the radiotherapy patients, and there was a non-significant change in the comparison between the control and the malignant groups.

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Keywords

Breast cancer, OGG1gene.

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