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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 2
First page : ( 632) Last page : ( 636)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00112.4

Phytochemical Screening, Antimicrobial Activity and Antimicrobial Finishing of Polyherbal Extract on Nonwoven Wound Dressing

Karpagam P1,*, Manonmani G2, Brindha D3

1Assistant Professor, Department of Costume Design and Fashion, PSG College of Arts and Science, Coimbatore, India

2Research Supervisor, Department of Home Science, Mother Teresa Women's University, Coimbatore, India

3Principal and Head, Department of Biochemistry, PSG College of Arts and Science, Coimbatore, India

*Corresponding Author E-mail: Karpagam.psg@gmail.com

Online published on 18 April, 2019.

Abstract

Terminalia bellerica, Withania somnifera, Madhuca longifolia and Sygyzium cumini was selected for the current study based on its potent antimicrobial activity. The poly herbal plant extract was tested against nine clinical bacterial strains that are responsible for the wound infections. The FTIR and GCMS studies of the poly herbal plant extract revealed the presence of functional groups such as phenols, alcohol, amines, carbonyl group and components responsible for antimicrobial properties respectively. The phytochemical analysis showed the presence of bioactive principles such as alkaloids, flavanoids, phenols, steroids and tannins. The poly herbal extract was then coated on the TencelR nonwoven fabric using pad-dry-cure method. The antimicrobial efficacy of the coated fabrics exhibited better inhibitory activity against all the test organisms under the standard AATCC 147. The coated fabric also showed 8 mm zone of inhibition against Candida albicans. The results recommend the use of poly herbal plant extract can potentially be used as a substitute to synthetic agents. Also, it can be employed in non-implantable medical textiles such as wound dressings to prevent the microbial infestation and also to reduce the bio burden in wound therapy.

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Keywords

Antibacterial susceptibility, Non-implantable, Nonwoven, Wound dressing, Wound infections.

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