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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 12
First page : ( 6157) Last page : ( 6164)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.01070.9

Pellets and Techniques of Pelletization

Manoharan Kishore, Bhaskaran Navya Ajitkumar, Kumar Lalit*

Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576 104, Udupi, Karnataka, India

*Corresponding Author E-mail: lk.kundlas@gmail.com

Online published on 24 February, 2020.

Abstract

Background

In the present day scenario, where novel drug delivery system and controlled drug delivery systems have been developed over the conventional oral solid dosage forms, pellets emerged as a versatile delivery system. Pelletization is a technique to obtain pellets or spherical particles having a dimensions between 0.5–1.5 mm. These multiparticulate systems are either compressed into tablets or filled into capsules.

Area covered

The following review provides a brief outline on pelletization. In this review, we have discussed on various parameters affecting pelletization, different techniques of pelletization and assessment of pellets.

Expert opinion

It is expected that the pellatizaiton is an effective and efficient approach which can help in improvement of absorption, bioavailability, stability, etc. Pellets can offer therapeutic advantages with effordable cost. Several studies are performed to address the limitations of numerous drugs.

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Keywords

Multiparticulate systems, pellets, pelletization, oral solid dosage, controlled drug delivery.

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