(34.200.218.187)
Users online: 2077    [ij] [ij] [ij] 
Email id
 

Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 12
First page : ( 6067) Last page : ( 6070)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.01053.9

Wound Healing Potential of Psidium guajava var. Pyrifera

Shetty Prerana2, Chacko Nimmy1,*, Alva Abhishiktha1, Kumar Vijay1, Kandige Prasanna Shama1, Gururaj M P1, joshi Himanshu1, souza Ullas Prakash D’1

1Department of Pharmacology, Nitte (Deemed to be University), Mangalore, Karnataka-575018, India

2Department of Pharmaceutical Chemistry, NGSMIPS, Nitte (Deemed to be University), Mangalore, Karnataka, 575018, India

*Corresponding Author E-mail: nimmychacko@nitte.edu.in

Online published on 24 February, 2020.

Abstract

Objective

The present study was carried out to investigate the wound healing potential of the extract of dried leaves of Psidium guajava in albino wistar rats.

Materials and methods

Aerial parts of Psidium guajava L. was collected, dried and extracted (maceration) using ethanol. Preliminary qualitative phytochemical screening was carried out. In-vivo models like excision, incision and dead space wound were employed in the study.

Result

Accelerated healing process, increase in the tensile strength and increase in the wet tissue weight as well as dry tissue weight were observed in the extract treated groups in excision, incision and dead space wound model respectively. Dose dependent and significant (p<0.05) wound healing activity in in-vivo study were obtained.

Conclusion

The results revealed promising wound healing potential of the plant Psidium guajava, compared to silver sulfadiazine used as the reference standard

Top

Keywords

Wound healing activity, excision, incision, dead space, tensile strength, wet and dry tissue weight. Collagenation, Neovascularization, re-epithelisation.

Top

  
║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
435,458,445 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.