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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 11
First page : ( 5477) Last page : ( 5478)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00950.8

Evaluation of Antiurolithiatic activity of Polyherbal formulation (Lithout Tablets) by In-vitro inhibition of Calcium Oxalate Crystallization

Mrs. Jagtap Pradnya N.*, Ms. Vyapari Bhagyashri R., Ms. Nimbalkar Yashashri H., Mr. Kale Sitaram V., Mr. Nigade Ganesh B.

Department of Pharmacology, PDEA's S.G.R.S. College of Pharmacy, Saswad, Pune-412301, (M.S.) India

*Corresponding Author E-mail: pnj1511@gmail.com

Online published on 9 April, 2020.

Abstract

The present study is to determine the inhibitory effect of prepared Lithout tablets for their antiurolithiatic activity. In this study we used the turbidimetric model. In this model the inhibitory effect of Lithout tablets were determined by adding solution of different concentrations of prepared polyherbal formulation in the solution of calcium chloride and sodium oxalate. The absorbance of this solution was taken at 620 nm for each minute till 10 minutes. The percentage inhibition of calcium oxalate crystallization was calculated. Study reveals that prepared Lithout tablets effectively reduce the crystallization of calcium oxalate in the solution. And thus it was concluding that the Lithout tablets produce significant antiurolithiatic activity.

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Keywords

Calcium oxalate, inhibition, tubidimetry, polyherbal tablets, antiurolithiatic.

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