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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 11
First page : ( 5320) Last page : ( 5324)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00922.3

Selection of Better Method for the Preparation of Nanoparticles by Applying Analytic Hierarchy Process

Saminathan C., Venkatesan P., Madhusudhan S.

Department of Pharmacy, Faculty of Engineering and Technology, Annamalai University, Annamalai Nagar, Tamilnadu, India, 608002

Online published on 9 April, 2020.

Abstract

The aim of present study was to choose the better technique to achieve reproducibility and consistency with good entrapment efficiency for the preparation of nanoparticles by employing Analytic Hierarchy Process as tool. A number of techniques are available for the preparation of nanoparticles. AHP technique was applied to make choice amongst alternative nanoencapsulation techniques (Solvent Evaporation Technique (SET)/Nano Precipitation Method (NPM)/Solvent Diffusion Method (SDM)/Salting Out Method (SOM)) and thereby opt the best technique. The solution of the problem involves finding the composite score that reflects the relative priorities of all the alternatives at the lowest level of the hierarchy. The composite score is used for the final ranking of the alternatives. The composite score favored the selection of SET (score=0.469) over NPM (score=0.365), SDM (score=0.174), SOM (score=0.076) for Nano encapsulation technique.

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Keywords

Analytical hierarchy Process, Multi Criteria Decision Making, Nanoencapsulation, Solvent Evaporation Technique, Nano Precipitation Method, Solvent Diffusion Method and Salting out Method.

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