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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 11
First page : ( 5167) Last page : ( 5170)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00894.1

The inhibitor effects of silver and zinc oxide Nanoparticles on Pantoea agglomerans isolated from patients with Hemodialysis.

Kadhum Duaa A.1, Mohammed Saif A.1, Abbas Mohammed K.2

1Middle Technical University, Baqubah Technical Institute, Pathologic analysis techniques Dept, Diyala, Iraq

2Middle Technical University, Baqubah Technical Institute, Public Health Techniques Dept, Diyala, Iraq

*Corresponding Author E-mail: nissakmch@gmail.com

Online published on 9 April, 2020.

Abstract

Pantoea agglomerans bacterium based on Enterobacteriaceae acts as an opportunistic pathogen in patients with immune compromised, causing sepsis, wound infections and urinary tract infections. Anoverall of80Hemodialysis catheters swaps was collected from patients attended to Hemodialysis unit-Baqubah teaching hospitalin Diyala province-IRAQ. P. agglomerans was diagnosed by using selective media and many biochemical tests then VITEK system used to confirm these isolates. Antibiotics susceptibility test was performed using Kerby-Bauermethod. Minimum inhibitory concentration for Zink O and Silver O nanoparticles was detected by using standard agar dilution method. More than48isolates, 10 (20.8%) belonging to P. agglomerans, were uniformly susceptible to Augmentin, Gentamycin, Chloramphenicol. All isolates were resisted to Amikacin and cephalexin. Most of these isolates showed multidrug-resistant against Antibiotics targeted. The MIC ranging value for ZnONPs were between (652–12500 μg/ml) while for AG NPs were(652–5000 μg/ml)

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Keywords

Pantoea agglomerans, ZnO NPs, Ag NPs, MIC.

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