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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 1
First page : ( 361) Last page : ( 366)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00066.0

A Comparative Study on Phytochemical Screening, Antioxidant and Antimicrobial Capacities of Leaf Extracts from Medicinal plants

Sundar Ranjitha Dhevi V.1, Sathiavelu Mythili2,*

1School of Biosciences and Technology, VIT University, Vellore-632014, Tamil Nadu, India

2Assistant Professor (Senior), School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore-632014, Tamil Nadu, India

*Corresponding Author E-mail: smythili@vit.ac.in

Online published on 16 March, 2019.

Abstract

The aim of this work is to investigate and compare the phytochemical screening, antioxidant and antimicrobial activities of plant crude extracts from leaves of four different medicinal plants Mukia maderaspatana, Cissus quadrangularis, Portulaca quadrifida, Pisonia Alba. Methanol and Petroleum ether solvent were used to prepare the crude extracts from leaves. Antioxidant and antimicrobial activities of different crude extracts were determined by DPPH method and agar disc diffusion method. Antibacterial activity was carried out against five different organisms (Escherichia coli (MTCC: 1687), Bacillus cereus (MTCC: 0430), Klebsiella pneumoniae (MTCC: 7028), Staphylococcus aureus(MTCC: 3160), Proteus mirabilis (MTCC: 3310). And the antifungal activity against A.niger (MTCC 281) and A.flavus (MTCC 10938). All the extracts showed a promising antibacterial activity. Hence, the outcomes of the present research suggest that the potential antioxidant and antimicrobial activity of these different plants may be responsible for its wide traditional use as medicine.

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Keywords

Medicinal plants, Antimicrobial activity, Antioxidant, DPPH, Phytochemical analysis.

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