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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 9
First page : ( 3983) Last page : ( 3989)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00732.1

Use of Doppler Echocardiography as a Prognostic Marker in Evaluating Hypertensive Patients with and without left Ventricular Hypertrophy-A Hospital Based Study in Vellore

Dr. Babu K Thirumal1, Nivetha R2, Das Raja3, Saraswathy Radha2,*

1Professor of Cardiology, Government Vellore Medical College Hospital, Vellore, Tamil Nadu, India

2120 TT Biomedical Genetics Research Lab (BMGRL), Dept. of Biomedical Sciences, School of Bio Sciences and Technology, VIT University, Vellore-632014, India

3School of Advanced Sciences, VIT University, Vellore-632014, India

*Corresponding Author E-mail: radhasaraswathy60@gmail.com

Online published on 20 December, 2018.

Abstract

Background

The number of individuals with hypertension in India is increasing rapidly, however, the awareness, detection, treatment and control rates are very poor. The incidence of cardiomyopathies such as Left ventricular Hypertrophy (LVH) is seen to be quite high in patients with hypertension. In addition to this, metabolic diseases like diabetes mellitus, obesity and hyperlipidemia may increase the incidence of cardiovascular changes such as Left ventricular Hypertrophy. LVH plays a prognostic risk factor in hypertensive patients.

Methods

M-mode echocardiography, Blood pressure measurements and biochemical analyses for all the patients-Hypertensive (n=25); Hypertensive with LVH (n=25); LVH (n=25) and Normotensive (n=25) were carried out. The statistical analyses were performed using MATLAB software.

Results

The high prevalence of LVH in Hypertensive patients on echocardiography implies that these patients require detailed cardiovascular evaluation despite absence of symptoms.

Conclusion

The Doppler echocardiography outcomes have shown to be useful substitute marker for prognosis and intervention studies. New Doppler echocardiographic techniques with much accuracy to investigate subclinical condition will benefit further for this group of patient at excessive cardiovascular risk.

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Keywords

Doppler echocardiography, Hypertension, Left ventricular Hypertrophy.

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