In Vitro cytotoxicity of L-Glutaminase against Hep-G2 cell lines
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Hepatocellular carcinoma (HCC) is one of the most common types of malignancies that carries poor prognosis worldwide. Accumulating evidences suggest the beneficial effects of amino acid-depleting enzymes in lowering the risk of various cancers. Herein, we investigated the in vitro antioxidant (DPPH) and anticancer effects of Lglutaminase produced by Idiomarina sediminum; H1695 against Hep-G2 cell lines by MTT assay. Collectively, these findings indicate a crucial role of L-glutaminase in liver cancer.
Hepatocellular carcinoma (HCC), Antioxidant, L-glutaminase, Hep-G2 cell line, 2, 2-diphenyl1-picrylhydrazyl (DPPH).