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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 5
First page : ( 1737) Last page : ( 1744)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00323.2

Factors of the complicated course of the myocardial infarction in men and women

Bedelbayeva Gulnara1, Nurmakhanova Zhannat2,*, Almukhambetov Murat1, Zarubekova Nazima1, Nuftieva Ainur1

1Department of Ambulance Urgent Medical Help, Kazakh National Medical University named after S.D. Asfendiyarov, Zheltoxsan Street, 129-32, Almaty, 50000, Kazakhstan

2Department of Therapy Postgraduate Education, Kazakh National Medical University named after S.D. Asfendiyarov, Zheltoxsan Street, 129-32, Almaty, 50000, Kazakhstan

*Corresponding Author E-mail: zhannatnurmakhanova@gmail.com

Online published on 21 August, 2018.


The coronary heart disease (CHD) and myocardial infarction (MI) are among the leading causes of death throughout the World. The purpose of the research wasto study the features of a myocardial infarction course in men and women and to develop ways of predicting lethal outcome and complicated course of a disease. Research was based on 121 patients (86 men and 35 women) with the confirmed diagnosis of MI. During hospitalization, men were tested for coronary angiography more often, than women. Coronary arteries disease was caused in men by damage of one vessel, whereas in women it was damage of one, two or three vessels and the left coronary artery (LCA) trunk. The hospital lethality for women was 2.5 times higher than in men and the most frequent cause of death both in men and women was acute cardiovascular insufficiency (ACVI), while men more often suffered from thromboembolia. Rhythm and patency disturbances affected the lethality in both men and women equally, but men were also influenced by age, MI localization and atherosclerosis intensity, while women had an acute heart failure, metabolic and electrolytic frustration. The data showed that the factors influencing the complicated course of MI in men and women are different. Acute heart failure, MI localization and coronary artery disease are more common for men. In women such factors are ST elevation myocardial infarction, ventricular rhythm disturbances during breakthrough, anemia and hypercreatininemia at admission.



Chronic heart failure, Complicated course, Coronary angiography, Coronary heart disease, Myocardial infarction.


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