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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 4
First page : ( 1467) Last page : ( 1474)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00273.1

Design and Characterization of Levofloxacin Orodispersible Tablets

Asha D.1, Jeganath S.2,*, Arjun U.V.N.V.2, Kumar Sathesh S.2

1Saastra College of Pharmaceutical Education and Research, Nellore. AP., India

2Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science, Technology And Advanced Studies (VISTAS), Pallavaram, Chennai-600117, India

*Corresponding Author E-mail: jeganaths@gmail.com

Online published on 24 July, 2018.

Abstract

In order to overcome the challenges of the solid unit dosage forms, Fast Dissolving Tablets (FDT) or orally disintegrating tablets (ODT) has emerged as alternative oral dosage forms. These novel types of tablets have the ability to dissolve more rapidly when compared to standard solid dosage forms. The main objective of the present study was to develop Oral dispersible tablet formulation containing 150mg of Levofloxacin for the treatment of a number of infections including infection of Joints and bones, respiratory tract infections, urinary tract infections, skin structural infections and typhoid fever etc. In our study, it was observed that all the values of pre-compression and post-compression studies were within the limits.

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Keywords

Oral Disintegrating Tablets, Levofloxacin, Superdisintegrants, Stability Studies.

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