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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 3
First page : ( 1270) Last page : ( 1274)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00236.6

Mechanism of action of Bone Morphogenic Protein 3 in the maintenance of Tissue Homeostasis

Dr. Kumar M.P. Santhosh1,*, Nandhini T.2

1Reader, Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Saveetha University, 162, Poonamallee High Road, Velappanchavadi, Chennai, 600077, Tamil Nadu, India

2Final year B.D.S. Saveetha Dental College

*Corresponding Author E-mail: santhoshsurgeon@gmail.com.

Online published on 7 July, 2018.

Abstract

Bone morphogenetic protein 3 (BMP 3), also known as osteogenin, is a protein in humans that is encoded by the BMP3 gene. It has the ability to regulate bone and cartilage development and it negatively regulates bone density. This article reviews the pathway in which bone morphogenic protein 3 acts upon and explains the mechanism of its action on the tissues.

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Keywords

Bone morphogenic protein 3, BMP 3, bone, cartilage, protein, receptor, signal.

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