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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 3
First page : ( 1097) Last page : ( 1100)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00206.8

Effect of Cranberry on biofilm formation by P. mirabilis isolated from Patients Suffering from Urinary tract Infections

Dr. Abdul-Lateef Lamees A.1,*, Dr. Hassan Emad2, Taha Abd-Alla Bactash Enas3

1Assist. Prof., Department of Microbiology, College of Medicine, Babylon University, Iraq

2Professor, Department of Surgery, College of Medicine, Babylon University, Iraq

3Al-Hilla surgery Teaching Hospital, Iraq

*Corresponding Author E-mail: dr.lamees.razzak@gmail.com

Online published on 7 July, 2018.


A total of (100) alkalineurine were obtained from a patient suffering from urinary tract infection from both sexes attended to Al-Hilla surgery Teaching Hospital during a period from September 2016 to December 2016 in Al-Hilla province. It was found that (23) P. mirabilis isolates were recovered where 14(60%) isolated obtained from patient with complicated urinary tract infection and 9 (39%) isolated obtained from patients with simple urinary tract infection from both sexes. Biofilm formation was also investigated using tissue culture plate, it was found the production of biofilm of P. mirabilis show that different potential capacity form biofilm, in complicated UTI, P. mirabilis is about 8(57%) which are strong former and the 6(42%) are mild former and 0(0%) in weak former of biofilm formation, So, in simple UTI P. mirabilis is about 0(0%) of P. mirabilis are strong former and the 5(55%) are mild former and 4(44%) in weak former of biofilm formation. Regard the effect of cranberry (5%) on biofilm formation was as wise studied; it was found that, the production biofilm of P. mirabilis show different potential capacity to form biofilm, the result of this study demonstrated that cranberry effectively reduced the viability of biofilm formation in complicated UTI. The biofilm formation was reduced as moderate to (28.57%), weak (71.42%) and no strong. So, in simple UTI the result was demonstrated that the biofilm production altered from (55%) to (0%).



Biofilm formation, Cranberry, UTI.


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