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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 12
First page : ( 5672) Last page : ( 5674)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.01027.2

The Role of Thyroid Dysfunction and The Importance of Conducting Regular Thyroid Function Tests in patients with PCOS: A Narrative Review

Dr. Aanandhi M. Vijey1,*, John Meha2

1Professor and Head of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, 600117

2Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai-600 117

*Corresponding Author E-mail: hodpchemistry@velsuniv.ac.in

Online published on 18 May, 2019.

Abstract

Polycystic Ovary Syndrome (PCOS) and thyroid pathology, the two endocrine abnormalities have been connected to each other since quite a long while, however, the majority of the scientists have researched the relationship amongst hypothyroidism and PCOS, a backward relationship of PCOS prompting thyroid brokenness is presently being tested into. Consequently this investigation went for investigating the likelihood of improvement of thyroid brokenness in ladies with PCOS. Thyroid hormones effectively affect the regenerative arrangement of the human female. Modification in thyroid capacity, especially hypothyroidism, can cause ovulatory brokenness and prompt impeded female richness. Hypothyroidism and PCOS are frequently joined by expanded serum free testosterone, luteinizing hormone (LH) and elevated cholesterol. At the point when the ovaries of hypothyroid women with PCOS have seen with an ultrasound, an expansion in ovarian volume and the presence of reciprocal multicystic ovaries are frequently obvious. At the point when thyroid hormone substitution treatment is started, notwithstanding settling thyroid hormone levels, ovarian sores relapse and ovarian volume are diminished. In this way ladies with PCOS could be at a hazard for the advancement of thyroid issue and biochemical screening of all the thyroid parameters including that of thyroid autoantibodies is of most extreme significance in such people.

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Keywords

PCOS, thyroid dysfunction, thyroid autoantibodies.

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