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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 12
First page : ( 5497) Last page : ( 5506)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.01001.6

Fabrication and Portrayal of Multifaceted Tasks of Biogenic Silver Nanoparticles obtained from Azima tetracantha. L

Paramasivam Geetha1,2,*, Subbiah Sankaralingam2, Paulraj Sugapriya Menaga1, Somasundaram Sivasankara Narayani3, Pandiarajan Jeyaraj1

1PG Department of Biotechnology, Ayya Nadar Janaki Ammal College, Sivakasi

2PG and Research Department of Botany, Saraswathi Narayanan College, Madurai

3PG Department of Microbiology, Ayya Nadar Janaki Ammal College, Sivakasi

*Corresponding Author E-mail: geethavasan78@gmail.com

Online published on 18 May, 2019.

Abstract

Nanotechnology is an ecofriendly technology, help to synthesis nanoparticles which is good and favorable for mankind. Nanoparticle synthesis has generating interest of researchers to investigate mechanism of metal ions uptake and bio-reduction in plants. In this present investigation we report the green synthesis of silver nanoparticles by using leaf extracts of medicinal plant Azima tetracantha. The biosynthesized silver nanoparticles were characterized with the help of UV-Spectrophotometry, SEM, FTIR and HPLC. The enhanced antibacterial activity of silver nanoparticles are active against human pathogenic microorganisms such as Escherichia coli, Seratia sp., Klebsiella sp., Pseudomonas sp., and Staphylococcus sp. based on zone of inhibition. Antioxidant activity of the extracts was analyzed as contents of total phenols, DPPH assay and Hydrogen Peroxide. The leaf extract of Azima tetracantha having great power in cytotoxic activity against human breast adenocarcinoma cell line (MCF7).

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Keywords

Azima tetracantha, UV-Spectrophotometry, FTIR, antimicrobial, DPPH, Hydrogen Peroxide, anticancer.

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