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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 12
First page : ( 5373) Last page : ( 5375)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00980.0

In vitro Antioxidant and Antidiabetic Activity of Supercritical Fluid extract of Leaves Ocimum sanctum L.

Lokhande V.Y.1,*, Dr. Yadav A.V.2

1Goverment College of Pharmacy, Karad, MS (India)

2Gourishankar Institute of Pharmaceutical Education and Research, Limb, Satara, MS (India)

*Corresponding Author E-mail: lokhande.vasant@gmail.com

Online published on 18 May, 2019.

Abstract

The antioxidant and anti-diabetic activity of supercritical CO2 extracts of Ocimum sanctum Ldried leaves obtained from plants grown in different areas of Satara. The antioxidant activity was made by the different assay DPPH, superoxide anion radical scavenging, nitric oxide scavenging activity methods and Anti-diabetic activity done by α inhibition method. The supercritical extracts of dried leaves of Ocimum sanctum Lconcentration (100–1000μg/ml)exhibited the highest activity.

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Keywords

Antioxidant activity, Anti-diabetic activity, Ocimum sanctum L, DPPH, NO scavenging activity, SOD activity.

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