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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 11
First page : ( 5191) Last page : ( 5196)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00948.4

Nanoemulsion: A Droplet Nanocarrier System for Enhancing Bioavailability of Poorly Water Soluble Drugs

Khan Wasim1,*, Dr. Ansari Vaseem Ahmad2, Dr. Hussain Zeashan3, Siddique Noor Fatima4

1Faculty of Pharmacy, Integral University, Lucknow, UP

2Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh. vaseem@iul.ac.in

3Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh. zeashanmgip@gmail.com

4Babasaheb Bhimrao Ambedkar University, Lucknow, Uttar Pradesh. noorfatima1510@gmail.com

*Corresponding Author E-mail: 92wasimkhan@gmail.com

Online published on 30 January, 2019.

Abstract

The approach for drug delivery has changed vastly with the use of nanotechnology, polymeric system and target drug delivery. One such a way to increase the bioavailability of a drug which is poorly water soluble, is nanoemulsion. Nanoemulsion is a system where one of immiscible liquid dispersed within another immiscible liquid as droplets leading to transparent emulsions. The surface characteristics of these droplets of nanoemulsion play an important role in the biological behavior of the formulation. The methods used for the preparation of nanoemulsions include high pressure homogenization, microfluidization, ultrasonication, and spontaneous emulsification. As application point of view nanoemulsions are crucial in different fields such as pharmaceutics, food technology and cosmetics. Here in this review, different features of nanoemulsion has been discussed along with the method of preparations, applications & advantages over other dosage forms.

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Keywords

NEs (nanoemulsions), high pressure homogenization, microfluidization.

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