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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 7
First page : ( 2183) Last page : ( 2188)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00385.7

A Prospective Observational Study on Drug Utilization Evaluation of Atorvastatin in Tertiary Care Hospital

Anis Fathima A. G.1,*, Dr. Rao Vara Prasanna2, Dr. Shanmugasundaram P.3

1Department of B Pharmacy Practice, Vels University, Pallavaram, Chennai-600117.

2Assistant Professor, Department of Pharmacy Practice, Vels University, Pallavaram, Chennai-600 117.

3Director, School of Pharmaceutical Sciences, Vels University, Pallavaram, Chennai-600117.

*Corresponding Author E-mail: anisilverl6@gmail.com

Online published on 17 October, 2017.

Abstract

Objectives

Our objectives are to study the rational use of Atorvastatin in patients in a tertiary care hospital.

METHODOLOGY

It was a prospective and observational study which was undertaken in hospital such as various departments, ESI hospital, Ayanavaram for a period of 6 months. A total of 110 patients were included in the study and were followed for the drug utilization evaluation of the study. This study criterion was carried out in In-patients of age greater than 35 years of either gender who are prescribed with HMG-COA reductase inhibitor Atorvastatin.

RESULTS

The Drug was found to be prescribed more in males [56%] compared to females [44%]. In the lipid profile study, all the different parameters like Total cholesterol: HDL ratio, HDL: LDL ratio and Triglycerides: HDL ratio was analyzed. Drug interactions were analyzed and reported.

Conclusion

We conclude that the drug use was found to be rational. Interventions for improving more accurate use of Atorvastatin should be implemented. Further studies from time to time are essential in drug utilization pattern and standard treatment guidelines to be circulated among practicing physicians.

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Keywords

Rational use, Body Mass Index, Lipid profile, Atorvastatin.

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